Semisynthesis and Biological Evaluation of Xanthone Amphiphilics as Selective, Highly Potent Antifungal Agents to Combat Fungal Resistance

Author:

Lin Shuimu123,Sin Wan Ling Wendy2,Koh Jun-Jie2,Lim Fanghui2,Wang Lin13,Cao Derong4,Beuerman Roger W.25,Ren Li13ORCID,Liu Shouping25ORCID

Affiliation:

1. School of Materials Science and Engineering, South China University of Technology, Guangzhou 510641, China

2. Singapore Eye Research Institute, The Academia, 20 College Road, Discovery Tower Level 6, Singapore 169856, Singapore

3. National Engineering Research Center for Tissue Restoration and Reconstruction, Guangzhou 510006, China

4. School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510641, China

5. SRP Neuroscience and Behavioral Disorders, Duke-NUS Graduate Medical School, Singapore 169857, Singapore

Funder

SingHealth Foundation

National Medical Research Council

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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