Structure-Based Design of Non-natural Macrocyclic Peptides That Inhibit Protein–Protein Interactions

Author:

Krüger Dennis M.12,Glas Adrian12,Bier David13,Pospiech Nicole1,Wallraven Kerstin1,Dietrich Laura12,Ottmann Christian34ORCID,Koch Oliver2ORCID,Hennig Sven15ORCID,Grossmann Tom N.125ORCID

Affiliation:

1. Chemical Genomics Centre of the Max Planck Society, Otto-Hahn-Str. 15, 44227 Dortmund, Germany

2. Faculty of Chemistry and Chemical Biology, TU Dortmund University, Otto-Hahn-Str. 6, 44227 Dortmund, Germany

3. Department of Chemistry, University of Duisburg-Essen, Universitätstr. 7, 45141 Essen, Germany

4. Department of Biomedical Engineering, Institute of Complex Molecular Systems, Eindhoven University of Technology, Den Dolech 2, 5612 AZ Eindhoven, The Netherlands

5. Department of Chemistry & Pharmaceutical Sciences, VU University Amsterdam, De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands

Funder

AstraZeneca

Bundesministerium f?r Bildung und Forschung

Merck KGaA

Bayer CropScience

Deutsche Forschungsgemeinschaft

Bayer HealthCare

Max-Planck-Gesellschaft

Boehringer Ingelheim

H2020 European Research Council

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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