Cyclic Analogues of the Chemerin C-Terminus Mimic a Loop Conformation Essential for Activating the Chemokine-like Receptor 1-Reference-Cited by-同舟云学术

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Cyclic Analogues of the Chemerin C-Terminus Mimic a Loop Conformation Essential for Activating the Chemokine-like Receptor 1

Published:2021-03-11 Issue:6 Volume:64 Page:3048-3058
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Fischer Tobias F.¹,Schoeder Clara T.²,Zellmann Tristan¹,Stichel Jan¹,Meiler Jens²³,Beck-Sickinger Annette G.¹^ORCID

Affiliation:

1. Institute of Biochemistry, Leipzig University, Brüderstraße 34, 04103 Leipzig, Germany

2. Center for Structural Biology, Department of Chemistry, Vanderbilt University, 465 21st Avenue South, Nashville, Tennessee37212, United States

3. Institute for Drug Discovery, Leipzig University Medical School, 04103 Leipzig, Germany

Funder

Max Kade Foundation

Deutsche Forschungsgemeinschaft

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c01804

Reference52 articles.

1. Specific Recruitment of Antigen-presenting Cells by Chemerin, a Novel Processed Ligand from Human Inflammatory Fluids

2. Chemerin—A new adipokine that modulates adipogenesis via its own receptor

3. The Expression and Regulation of Chemerin in the Epidermis

4. Chemerin Activation by Serine Proteases of the Coagulation, Fibrinolytic, and Inflammatory Cascades

5. Processing, signaling, and physiological function of chemerin

Cited by 11 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Structural basis of G protein–Coupled receptor CMKLR1 activation and signaling induced by a chemerin-derived agonist;PLOS Biology;2023-12-06

2. Discovery of 3-Phenyl Indazole-Based Novel Chemokine-like Receptor 1 Antagonists for the Treatment of Psoriasis;Journal of Medicinal Chemistry;2023-10-26

3. Stable Binding of Full‐Length Chemerin Is Driven by Negative Charges in the CMKLR1 N Terminus;ChemBioChem;2023-08-09

4. Structural basis of CMKLR1 signaling induced by chemerin9;2023-06-10

5. Cryo-EM structure of the human chemerin receptor 1–Gi protein complex bound to the C-terminal nonapeptide of chemerin;Proceedings of the National Academy of Sciences;2023-03-07

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