Carboxylesterase Notum Is a Druggable Target to Modulate Wnt Signaling-Reference-Cited by-同舟云学术

Carboxylesterase Notum Is a Druggable Target to Modulate Wnt Signaling

Published:2021-03-30 Issue:8 Volume:64 Page:4289-4311
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bayle Elliott D.¹²,Svensson Fredrik¹²^ORCID,Atkinson Benjamin N.¹,Steadman David¹^ORCID,Willis Nicky J.¹,Woodward Hannah L.¹^ORCID,Whiting Paul¹,Vincent Jean-Paul²,Fish Paul V.¹²^ORCID

Affiliation:

1. Alzheimer’s Research UK UCL Drug Discovery Institute, University College London, Cruciform Building, Gower Street, London WC1E 6BT, U.K.

2. The Francis Crick Institute, 1 Midland Road, Kings Cross, London NW1 1AT, U.K.

Funder

Medical Research Council

Francis Crick Institute

Wellcome Trust

Cancer Research UK

Alzheimer's Research UK

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c01974

Reference129 articles.

1. Effect of the wingless (wg1) mutation on wing and haltere development in Drosophila melanogaster

2. Mutations affecting segment number and polarity in Drosophila

3. Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome

4. Generating Cellular Diversity and Spatial Form: Wnt Signaling and the Evolution of Multicellular Animals

5. Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases

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