Discovery of a Potent Adenine–Benzyltriazolo–Pleuromutilin Conjugate with Pronounced Antibacterial Activity against MRSA-Reference-Cited by-同舟云学术

Discovery of a Potent Adenine–Benzyltriazolo–Pleuromutilin Conjugate with Pronounced Antibacterial Activity against MRSA

Published:2020-12-16 Issue:24 Volume:63 Page:15693-15708
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Heidtmann Christoffer V.¹,Voukia Faidra¹,Hansen Louise N.¹,Sørensen Stine H.¹,Urlund Brian¹,Nielsen Salli¹,Pedersen Mona¹,Kelawi Noor¹,Andersen Brian N.¹,Pedersen Maria¹,Reinholdt Peter¹^ORCID,Kongsted Jacob¹^ORCID,Nielsen Carsten U.¹^ORCID,Klitgaard Janne K.²³,Nielsen Poul¹^ORCID

Affiliation:

1. Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, 5230 Odense M, Denmark

2. Department of Biochemistry and Molecular Biology, Research Unit of Molecular Microbiology, University of Southern Denmark, 5230 Odense M, Denmark

3. Institute of Clinical Research, Research Unit of Clinical Microbiology, University of Southern Denmark, 5230 Odense M, Denmark

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c01328

Reference41 articles.

1. The Crisis in Antibiotic Resistance

2. The antibiotic resistance crisis, with a focus on the United States

3. Pleuromutilins: Potent Drugs for Resistant Bugs—Mode of Action and Resistance

4. Antibiotic Substances From Basidiomycetes: VIII. Pleurotus Multilus (Fr.) Sacc. and Pleurotus Passeckerianus Pilat

5. Antibiotic Substances from Basidiomycetes: IX. Drosophila Subtarata. (Batsch Ex Fr.) Quel.

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