Discovery of the Potent, Selective, Orally Available CXCR7 Antagonist ACT-1004-1239-Reference-Cited by-同舟云学术

Discovery of the Potent, Selective, Orally Available CXCR7 Antagonist ACT-1004-1239

Published:2020-12-14 Issue:24 Volume:63 Page:15864-15882
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Richard-Bildstein Sylvia¹^ORCID,Aissaoui Hamed¹,Pothier Julien¹,Schäfer Gabriel¹^ORCID,Gnerre Carmela¹,Lindenberg Eleanor¹,Lehembre François¹,Pouzol Laetitia¹,Guerry Philippe¹^ORCID

Affiliation:

1. Drug Discovery, Idorsia Pharmaceuticals Ltd., Hegenheimermattweg 91, Allschwil CH-4123, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c01588

Reference44 articles.

1. A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development

2. Pattern of CXCR7 Gene Expression in Mouse Brain Under Normal and Inflammatory Conditions

3. The Chemokine SDF-1/CXCL12 Binds to and Signals through the Orphan Receptor RDC1 in T Lymphocytes

4. CXCR7 Functions as a Scavenger for CXCL12 and CXCL11

5. Cxcr7 Controls Neuronal Migration by Regulating Chemokine Responsiveness

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