Mithramycin 2′-Oximes with Improved Selectivity, Pharmacokinetics, and Ewing Sarcoma Antitumor Efficacy-Reference-Cited by-同舟云学术

Mithramycin 2′-Oximes with Improved Selectivity, Pharmacokinetics, and Ewing Sarcoma Antitumor Efficacy

Published:2020-11-16 Issue:22 Volume:63 Page:14067-14086
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Liu Yang¹²,Eckenrode Joseph M.¹,Zhang Yinan¹²^ORCID,Zhang Jianjun¹²,Hayden Reiya C.¹,Kyomuhangi Annet¹,Ponomareva Larissa V.¹²,Cui Zheng¹,Rohr Jürgen¹,Tsodikov Oleg V.¹,Van Lanen Steven G.¹^ORCID,Shaaban Khaled A.¹²^ORCID,Leggas Markos¹²^ORCID,Thorson Jon S.¹²^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536, United States

2. Center for Pharmaceutical Research and Innovation, College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536, United States

Funder

National Center for Advancing Translational Sciences

National Cancer Institute

National Institute of Allergy and Infectious Diseases

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine