Novel 2-Substituted 3-Hydroxy-1,6-dimethylpyridin-4(1H)-ones as Dual-Acting Biofilm Inhibitors of Pseudomonas aeruginosa
Author:
Affiliation:
1. College of Pharmacy, Jinan University, Guangzhou 510632, P. R. China
Funder
National Natural Science Foundation of China
Natural Science Foundation of Guangdong Province
Guangzhou Municipality
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c00763
Reference59 articles.
1. Modulation of Host Biology by Pseudomonas aeruginosa Quorum Sensing Signal Molecules: Messengers or Traitors
2. Structure–Activity Relationships of 6- and 8-Gingerol Analogs as Anti-Biofilm Agents
3. A quorum sensing-associated virulence gene of Pseudomonas aeruginosa encodes a LysR-like transcription regulator with a unique self-regulatory mechanism
4. The Pseudomonas aeruginosa quinolone signal molecule overcomes the cell density-dependency of the quorum sensing hierarchy, regulates rhl-dependent genes at the onset of stationary phase and can be produced in the absence of LasR
5. 4-Quinolone signalling in Pseudomonas aeruginosa: Old molecules, new perspectives
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