Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery-Reference-Cited by-同舟云学术

Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery

Published:2021-04-28 Issue:9 Volume:64 Page:5730-5745
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Huecas Sonia¹,Araújo-Bazán Lidia¹,Ruiz Federico M.¹,Ruiz-Ávila Laura B.¹,Martínez R. Fernando²^ORCID,Escobar-Peña Andrea²,Artola Marta²^ORCID,Vázquez-Villa Henar²^ORCID,Martín-Fontecha Mar²,Fernández-Tornero Carlos¹,López-Rodríguez María L.²^ORCID,Andreu José M.¹^ORCID

Affiliation:

1. Centro de Investigaciones Biológicas Margarita Salas, CSIC, Ramiro de Maeztu 9, 28040 Madrid, Spain

2. Dept. Química Orgánica, Facultad de Ciencias Químicas, UCM, Avda. Complutense s/n, 28040 Madrid, Spain

Funder

Ministerio de Ciencia e Innovaci?n

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c02207

Reference56 articles.

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4. Centers for Disease Control and Prevention. 2019 Antibiotic Resistance Threats Report; WHO, 2019. Can be found under: https://www.cdc.gov/drugresistance/biggest-threats.html.

5. FtsZ ring structure associated with division in Escherichia coli

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