Design, Synthesis, and Evaluation of (2-Aminocyclopropyl)phenyl Derivatives as Novel Positron Emission Tomography Imaging Agents for Lysine-Specific Demethylase 1 in the Brain-Reference-Cited by-同舟云学术

Design, Synthesis, and Evaluation of (2-Aminocyclopropyl)phenyl Derivatives as Novel Positron Emission Tomography Imaging Agents for Lysine-Specific Demethylase 1 in the Brain

Published:2021-03-17 Issue:7 Volume:64 Page:3780-3793
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hattori Yasushi¹^ORCID,Matsuda Satoru¹,Baba Rina¹,Matsumiya Kouta¹,Iwasaki Shinji¹,Constantinescu Cristian C.²,Morley Thomas J.²,Carroll Vincent M.²,Papin Caroline²,Gouasmat Alexandra²,Alagille David³,Tamagnan Gilles³,Koike Tatsuki¹^ORCID

Affiliation:

1. Research, Takeda Pharmaceutical Company Limited, 26-1 Muraoka-Higashi 2-Chome, Fujisawa, Kanagawa 251-8555, Japan

2. Invicro LLC, 60 Temple Street, Suite 8A, New Haven, Connecticut 06518, United States

3. XingImaging LLC, 760 Temple Street, New Haven, Connecticut 06510, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c01937

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