Design, Synthesis, and Biological Evaluation of New Peripheral 5HT2A Antagonists for Nonalcoholic Fatty Liver Disease

Author:

Kim Minhee1ORCID,Hwang Inseon2,Pagire Haushabhau S.1,Pagire Suvarna H.1,Choi Wonsuk2,Choi Won Gun2,Yoon Jihyeon1,Lee Won Mi1,Song Jin Sook3,Yoo Eun Kyung4,Lee Seung Mi4,Kim Mi-jin4,Bae Myung Ae3,Kim Dooseop5,Lee Heejong5,Lee Eun-Young5,Jeon Jae-Han46,Lee In-Kyu46,Kim Hail2,Ahn Jin Hee15ORCID

Affiliation:

1. Department of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea

2. Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon 34141, Republic of Korea

3. Bio & Drug Discovery Division, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea

4. Leading-edge Research Center for Drug Discovery and Development for Diabetes and Metabolic Disease, Kyungpook National University Hospital, Daegu 41010, Republic of Korea

5. R&D center, JD Bioscience, 123 Cheomdan-dwagiro, Buk-gu, Gwangju 61005, Republic of Korea

6. Department of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu 41944, Republic of Korea

Funder

Korea Health Industry Development Institute

National Research Foundation of Korea

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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