Discovery of Orally Bioavailable Purine-Based Inhibitors of the Low-Molecular-Weight Protein Tyrosine Phosphatase
Author:
Affiliation:
1. Department of Medicine, University of California, San Diego, La Jolla, California 92037, United States
2. Conrad Prebys Center for Chemical Genomics, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California 92037, United States
Funder
American Diabetes Association
National Institute of Diabetes and Digestive and Kidney Diseases
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c02126
Reference36 articles.
1. Putting the Brakes on Insulin Signaling
2. Insulin Receptor Signaling in Normal and Insulin-Resistant States
3. A review of the efficacy and safety of oral antidiabetic drugs
4. Insulin signalling and the regulation of glucose and lipid metabolism
5. A cascade of tyrosine autophosphorylation in the beta-subunit activates the phosphotransferase of the insulin receptor.
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