The Discovery of Novel ACA Derivatives as Specific TRPM2 Inhibitors that Reduce Ischemic Injury Both In Vitro and In Vivo-Reference-Cited by-同舟云学术

The Discovery of Novel ACA Derivatives as Specific TRPM2 Inhibitors that Reduce Ischemic Injury Both In Vitro and In Vivo

Published:2021-03-30 Issue:7 Volume:64 Page:3976-3996
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhang Han¹,Yu Peilin²,Lin Hongwei³,Jin Zefang¹,Zhao Siqi¹,Zhang Yi³,Xu Qingxia¹,Jin Hongwei¹,Liu Zhenming¹^ORCID,Yang Wei³,Zhang Liangren¹^ORCID

Affiliation:

1. State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, P. R. China

2. Department of Toxicology, and Department of Medical Oncology of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310058, Zhejiang, P. R. China

3. Department of Biophysics, and Department of Neurosurgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310058, P. R. China

Funder

Ministry of Science and Technology of the People's Republic of China

Natural Science Foundation of Beijing Municipality

National Natural Science Foundation of China

Ningxia Hui Autonomous Region

Zhejiang Province

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c02129