Insights into PPARγ Phosphorylation and Its Inhibition Mechanism-Reference-Cited by-同舟云学术

Insights into PPARγ Phosphorylation and Its Inhibition Mechanism

Published:2020-04-02 Issue:9 Volume:63 Page:4811-4823
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Montanari Roberta¹,Capelli Davide¹,Yamamoto Keiko²^ORCID,Awaishima Hirono²,Nishikata Kimina²,Barendregt Arjan³,Heck Albert J. R.³^ORCID,Loiodice Fulvio⁴^ORCID,Altieri Fabio⁵,Paiardini Alessandro⁵,Grottesi Alessandro⁶,Pirone Luciano⁷,Pedone Emilia⁷,Peiretti Franck⁸^ORCID,Brunel Jean Michel⁹^ORCID,Itoh Toshimasa²^ORCID,Pochetti Giorgio¹^ORCID

Affiliation:

1. Istituto di Cristallografia, Consiglio Nazionale delle Ricerche, Via Salaria km. 29.300, 00015 Monterotondo Stazione, Rome, Italy

2. Laboratory of Drug Design and Medicinal Chemistry, Showa Pharmaceutical University, 3-3165 Higashi-tamagawagakuen, Machida, Tokyo 194-8543, Japan

3. Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Science4Life, University of Utrecht, Padualaan 8, 3584 CH Utrecht, The Netherlands

4. Department of Pharmacy & Drug Sciences, University of Bari “Aldo Moro”, Via Orabona 4, 70125 Bari, Italy

5. Department of Biochemical Sciences “A. Rossi Fanelli”, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy

6. CINECA Consorzio Interuniversitario, Sede di Roma, 00185 Rome, Italy

7. Institute of Biostructures and Bioimaging, CNR, Via Mezzocannone 16, 80134 Naples, Italy

8. Faculté de Médecine, Aix Marseille Université, INSERM, INRAE, C2VN, 13385 Marseille, France

9. Aix Marseille Université, INSERM, SSA, MCT, 13385 Marseille, France

Funder

Associazione Italiana per la Ricerca sul Cancro

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c00048

Reference55 articles.

1. The Mechanisms of Action of PPARs

2. PPARs: therapeutic targets for metabolic disease

3. Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors and

4. Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

5. PPARs and the complex journey to obesity

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