The Most Common Functional Groups in Bioactive Molecules and How Their Popularity Has Evolved over Time-Reference-Cited by-同舟云学术

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The Most Common Functional Groups in Bioactive Molecules and How Their Popularity Has Evolved over Time

Published:2020-07-14 Issue:15 Volume:63 Page:8408-8418
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ertl Peter¹^ORCID,Altmann Eva¹^ORCID,McKenna Jeffrey M.²

Affiliation:

1. Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Basel CH-4056, Switzerland

2. Global Discovery Chemistry, Novartis Institutes for BioMedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c00754

Reference83 articles.

1. PATAI'S Chemistry of Functional Groups

2. ZINC 15 – Ligand Discovery for Everyone

3. New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays

4. Rules for Identifying Potentially Reactive or Promiscuous Compounds

5. The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates

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