Nature-Inspired (di)Azine-Bridged Bisindole Alkaloids with Potent Antibacterial In Vitro and In Vivo Efficacy against Methicillin-Resistant Staphylococcus aureus-Reference-Cited by-同舟云学术

Nature-Inspired (di)Azine-Bridged Bisindole Alkaloids with Potent Antibacterial In Vitro and In Vivo Efficacy against Methicillin-Resistant Staphylococcus aureus

Published:2020-10-26 Issue:21 Volume:63 Page:12623-12641
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Rehberg Nidja¹,Sommer Gereon A.²,Drießen Daniel²,Kruppa Marco²,Adeniyi Emmanuel T.¹,Chen Shang³^ORCID,Wang Lin¹,Wolf Karina¹,Tasch Boris O. A.²,Ioerger Thomas R.⁴,Zhu Kui³^ORCID,Müller Thomas J. J.²,Kalscheuer Rainer¹^ORCID

Affiliation:

1. Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University Düsseldorf, Universitätsstr. 1, 40225 Düsseldorf, Germany

2. Institute of Organic Chemistry and Macromolecular Chemistry, Heinrich Heine University Düsseldorf, Universitätsstr. 1, D-40225 Düsseldorf, Germany

3. Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, No. 2 Yuanmingyuan West Road, Beijing 100193, China

4. Department of Computer Science, Texas A&M University, 710 Ross St., College Station, Texas 77843, United States

Funder

Deutsche Forschungsgemeinschaft

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c00826

Reference42 articles.

1. O′Neill, J. Review on antimicrobial resistance: tackling a crisis for the health and wealth of nations; https://amr-review.org/sites/default/files/SECURING%20NEW%20DRUGS%20FOR%20FUTURE%20GENERATIONS%20FINAL%20WEB_0.pdf 2015 (accessed Sept 23, 2020).

2. WHO, W. H. O. Global action plan on antimicrobial resistance; http://www.who.int/antimicrobial-resistance/global-action-plan/en 2015 (accessed Sept 23, 2020).

3. Staphylococcus aureusInfections

4. Methicillin-resistant Staphylococcus aureus: an overview of basic and clinical research

5. Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019

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