Exploration of TRPM8 Binding Sites by β-Carboline-Based Antagonists and Their In Vitro Characterization and In Vivo Analgesic Activities-Reference-Cited by-同舟云学术

Exploration of TRPM8 Binding Sites by β-Carboline-Based Antagonists and Their In Vitro Characterization and In Vivo Analgesic Activities

Published:2020-07-29 Issue:17 Volume:63 Page:9672-9694
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bertamino Alessia¹^ORCID,Ostacolo Carmine²^ORCID,Medina Alicia³,Di Sarno Veronica¹,Lauro Gianluigi¹^ORCID,Ciaglia Tania¹,Vestuto Vincenzo¹,Pepe Giacomo¹^ORCID,Basilicata Manuela Giovanna¹,Musella Simona⁴,Smaldone Gerardina¹,Cristiano Claudia²,Gonzalez-Rodriguez Sara³,Fernandez-Carvajal Asia³,Bifulco Giuseppe¹^ORCID,Campiglia Pietro¹⁴^ORCID,Gomez-Monterrey Isabel²^ORCID,Russo Roberto²

Affiliation:

1. Department of Pharmacy, University of Salerno, Via G. Paolo II 132, 84084 Fisciano, Salerno, Italy

2. Department of Pharmacy, University Federico II of Naples, Via D. Montesano 49, 80131 Naples, Italy

3. IDiBE, Universitas Miguel Herna′ndez, Avda de la Universidad, 032020 Elche, Spain

4. European Biomedical Research Institute (EBRIS), Via S. De Renzi 50, 84125 Salerno, Italy

Funder

Regione Campania

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

http://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c00816

Reference77 articles.

1. The thermo-TRP ion channel family: properties and therapeutic implications

2. The menthol receptor TRPM8 is the principal detector of environmental cold

3. Identification of a cold receptor reveals a general role for TRP channels in thermosensation

4. A TRP Channel that Senses Cold Stimuli and Menthol

5. TRPM8, a Sensor for Mild Cooling in Mammalian Sensory Nerve Endings

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