Analogues of the Herbicide, N-Hydroxy-N-isopropyloxamate, Inhibit Mycobacterium tuberculosis Ketol-Acid Reductoisomerase and Their Prodrugs Are Promising Anti-TB Drug Leads-Reference-Cited by-同舟云学术

Analogues of the Herbicide, N-Hydroxy-N-isopropyloxamate, Inhibit Mycobacterium tuberculosis Ketol-Acid Reductoisomerase and Their Prodrugs Are Promising Anti-TB Drug Leads

Published:2021-01-29 Issue:3 Volume:64 Page:1670-1684
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kandale Ajit¹,Patel Khushboo¹,Hussein Waleed M.¹,Wun Shun Jie¹,Zheng Shan¹,Tan Lendl¹^ORCID,West Nicholas P.¹^ORCID,Schenk Gerhard¹²³,Guddat Luke W.¹^ORCID,McGeary Ross P.¹^ORCID

Affiliation:

1. School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia Campus, Brisbane, Queensland 4072, Australia

2. Sustainable Minerals Institute, The University of Queensland, St Lucia Campus, Brisbane, Queensland 4072, Australia

3. Australian Institute of Bioengineering and Nanotechnology, The University of Queensland, St Lucia Campus, Brisbane, Queensland 4072, Australia

Funder

National Health and Medical Research Council

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c01919

Reference45 articles.

1. Global Tuberculosis Report, 2019. https://www.who.int/teams/global-tuberculosis-programme/tb-reports/global-report-2019 (accessed Nov 6, 2020).

2. Classification of drugs to treat multidrug-resistant tuberculosis (MDR-TB): evidence and perspectives

3. Recent updates on drug resistance in Mycobacterium tuberculosis

4. Inhibitors of branched-chain amino acid biosynthesis as potential antituberculosis agents

5. Biosynthesis of Branched Chain Amino Acids: From Test Tube to Field.

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