PF-07059013: A Noncovalent Modulator of Hemoglobin for Treatment of Sickle Cell Disease-Reference-Cited by-同舟云学术

PF-07059013: A Noncovalent Modulator of Hemoglobin for Treatment of Sickle Cell Disease

Published:2020-12-24 Issue:1 Volume:64 Page:326-342
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gopalsamy Ariamala¹,Aulabaugh Ann E.²,Barakat Amey³,Beaumont Kevin C.⁴,Cabral Shawn²,Canterbury Daniel P.²,Casimiro-Garcia Agustin¹^ORCID,Chang Jeanne S.²,Chen Ming Z.²,Choi Chulho²,Dow Robert L.¹^ORCID,Fadeyi Olugbeminiyi O.²,Feng Xidong²,France Scott P.²^ORCID,Howard Roger M.²^ORCID,Janz Jay M.³,Jasti Jayasankar²,Jasuja Reema³,Jones Lyn H.¹^ORCID,King-Ahmad Amanda⁵,Knee Kelly M.³,Kohrt Jeffrey T.²,Limberakis Chris²,Liras Spiros¹^ORCID,Martinez Carlos A.⁶,McClure Kim F.¹,Narayanan Arjun¹,Narula Jatin⁴,Novak Jonathan J.⁵,O’Connell Thomas N.²,Parikh Mihir D.²,Piotrowski David W.²^ORCID,Plotnikova Olga²,Robinson Ralph P.²^ORCID,Sahasrabudhe Parag V.²,Sharma Raman⁵,Thuma Benjamin A.²,Vasa Dipy⁷,Wei Liuqing²,Wenzel A. Zane²,Withka Jane M.²,Xiao Jun²,Yayla Hatice G.²

Affiliation:

1. Pfizer Medicine Design, Pfizer Worldwide Research and Development, Cambridge, Massachusetts 02139, United States

2. Pfizer Medicine Design, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States

3. Rare Diseases Research Unit, Pfizer Worldwide Research and Development, Cambridge, Massachusetts 02139, United States

4. Primary Pharmacology Group, Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Cambridge, Massachusetts 02139, United States

5. Primary Pharmacology Group, Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States

6. Medicinal Sciences, Pfizer Worldwide Research and Development, Groton, Connecticut 06340, United States

7. Drug Product Design, Pfizer Worldwide Research and Development, Cambridge, Massachusetts 02139, United States

Funder

Pfizer

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

http://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c01518

Reference53 articles.

1. Global epidemiology of haemoglobin disorders and derived service indicators