Synthesis of Mitochondria-Anchored Nitroimidazoles with a Versatile NIR Fluorophore for Hypoxic Tumor-Targeting Imaging and Chemoradiotherapy-Reference-Cited by-同舟云学术

Synthesis of Mitochondria-Anchored Nitroimidazoles with a Versatile NIR Fluorophore for Hypoxic Tumor-Targeting Imaging and Chemoradiotherapy

Published:2021-03-10 Issue:6 Volume:64 Page:3381-3391
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Chen Sha¹²,Yu Songtao³^ORCID,Du Zaizhi¹,Huang Xie¹,He Meng²,Long Shuang¹,Liu Jing¹,Lan Yu⁴,Yang Dong⁴,Wang Hao⁴,Li Shuhui²,Chen An²,Hao Yuhui¹,Su Yongping¹,Wang Changning⁴^ORCID,Luo Shenglin¹^ORCID

Affiliation:

1. State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Combined Injury, Chongqing Engineering Research Center for Nanomedicine, College of Preventive Medicine, Third Military Medical University (Army Medical University), 30 Gaotanyan Street, Shapingba District, Chongqing 400038, People’s Republic of China

2. Department of Clinical Biochemistry, Laboratory Sciences, Third Military Medical University (Army Medical University), 30 Gaotanyan Street, Shapingba District, Chongqing 400038, People’s Republic of China

3. Department of Oncology, Southwest Hospital, Third Military Medical University (Army Medical University), 30 Gaotanyan Street, Shapingba District, Chongqing 400038, People’s Republic of China

4. Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Charlestown, Massachusetts 02129, United States

Funder

Third Military Medical University

China Scholarship Council

National Natural Science Foundation of China

Chongqing Youth Talent Project

Military Logistics

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c02250