Evaluation of the Pharmacophoric Role of the O–O Bond in Synthetic Antileishmanial Compounds: Comparison between 1,2-Dioxanes and Tetrahydropyrans-Reference-Cited by-同舟云学术

Evaluation of the Pharmacophoric Role of the O–O Bond in Synthetic Antileishmanial Compounds: Comparison between 1,2-Dioxanes and Tetrahydropyrans

Published:2020-10-22 Issue:21 Volume:63 Page:13140-13158
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ortalli Margherita¹,Varani Stefania¹²,Cimato Giorgia¹,Veronesi Ruben³,Quintavalla Arianna³⁴^ORCID,Lombardo Marco³⁴^ORCID,Monari Magda³,Trombini Claudio³⁴

Affiliation:

1. Unit of Clinical Microbiology, Regional Reference Centre for Microbiological Emergencies (CRREM), St. Orsola-Malpighi University Hospital, Via Massarenti 9, 40138 Bologna, Italy

2. Department of Experimental, Diagnostic and Specialty Medicine, Alma Mater Studiorum - University of Bologna, Via Massarenti 9, 40138 Bologna, Italy

3. Department of Chemistry “G. Ciamician”, Alma Mater Studiorum - University of Bologna Via Selmi 2, 40126 Bologna, Italy

4. Centro Interuniversitario di Ricerca sulla Malaria (CIRM) - Italian Malaria Network (IMN), University of Milan, 20100 Milan, Italy

Funder

Ministero dell?Istruzione, dell?Universit? e della Ricerca

Universit? di Bologna

Fondazione Carisbo

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

http://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c01589