Pyrazole Agonist of the Apelin Receptor Improves Symptoms of Metabolic Syndrome in Mice-Reference-Cited by-同舟云学术

Pyrazole Agonist of the Apelin Receptor Improves Symptoms of Metabolic Syndrome in Mice

Published:2021-03-11 Issue:6 Volume:64 Page:3006-3025
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Narayanan Sanju¹,Wang Shaobin¹,Vasukuttan Vineetha¹,Vyas Devambatla Ravi Kumar²,Dai Donghua²,Jin Chunyang¹^ORCID,Snyder Rodney¹,Laudermilk Lucas¹,Runyon Scott P.¹,Maitra Rangan¹^ORCID

Affiliation:

1. Center for Drug Discovery, RTI International, Research Triangle Park, Durham, North Carolina 27709, United States

2. Sterling Pharma Solutions Limited, Sheldon Drive, Cary, North Carolina 27513, United States

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c01448

Reference51 articles.

1. Recent advances in managing/understanding the metabolic syndrome

2. The Role of Apelin in Cardiovascular Diseases, Obesity and Cancer

3. International Union of Basic and Clinical Pharmacology. LXXIV. Apelin Receptor Nomenclature, Distribution, Pharmacology, and Function

4. Regulation of the Apelinergic System and Its Potential in Cardiovascular Disease: Peptides and Small Molecules as Tools for Discovery

5. Identification and pharmacological properties of E339–3D6, the first nonpeptidic apelin receptor agonist

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