Synthesis and Structure–Activity Relationship of Dual-Stage Antimalarial Pyrazolo[3,4-b]pyridines-Reference-Cited by-同舟云学术

Synthesis and Structure–Activity Relationship of Dual-Stage Antimalarial Pyrazolo[3,4-b]pyridines

Published:2020-09-18 Issue:20 Volume:63 Page:11902-11919
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Eagon Scott¹^ORCID,Hammill Jared T.²,Sigal Martina³,Ahn Kevin J.¹,Tryhorn Julia E.¹,Koch Grant⁴,Belanger Briana¹,Chaplan Cory A.¹,Loop Lauren¹,Kashtanova Anna S.¹,Yniguez Kenya⁵,Lazaro Horacio⁶,Wilkinson Steven P.¹,Rice Amy L.²,Falade Mofolusho O.²,Takahashi Rei¹,Kim Katie¹,Cheung Ashley¹,DiBernardo Celine¹,Kimball Joshua J.⁶,Winzeler Elizabeth A.⁷^ORCID,Eribez Korina⁷,Mittal Nimisha⁷,Gamo Francisco-Javier⁸,Crespo Benigno⁸,Churchyard Alisje⁹,García-Barbazán Irene⁹,Baum Jake⁹,Anderson Marc O.¹⁰^ORCID,Laleu Benoît¹¹^ORCID,Guy R. Kiplin²^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, California Polytechnic State University, San Luis Obispo, California 93407, United States

2. Department of Pharmaceutical Sciences, University of Kentucky , Lexington, Kentucky 40508, United States

3. Department of Chemical Biology and Therapeutics, St Jude Children’s Research Hospital, Memphis, Tennessee 38105, United States

4. Department of Chemistry and Biochemistry, University of California Santa Cruz, Santa Cruz, California 95064, United States

5. SRI International, 333 Ravenswood Avenue, Menlo Park, California 94025, United States

6. Promega Biosciences, 277 Granada Drive, San Luis Obispo, California 93401, United States

7. School of Medicine, University of California San Diego, La Jolla, California 92093, United States

8. GlaxoSmithKline, Global Health, DDW, Tres Cantos, Madrid 28760, Spain

9. Department of Life Sciences, Imperial College London, South Kensington, London SW7 2AZ, United Kingdom

10. Department of Chemistry and Biochemistry, San Francisco State University, San Francisco, California 94132, United States

11. Medicines for Malaria Venture (MMV), P.O. Box 1826, 20, Route de Pré-Bois, Geneva 1215, Switzerland

Funder

California Polytechnic State University, San Luis Obispo

Wellcome

Medicines for Malaria Venture

Bill and Linda Frost Fund

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c01152

Reference61 articles.

1. Medical need, scientific opportunity and the drive for antimalarial drugs

2. The Open Access Malaria Box: A Drug Discovery Catalyst for Neglected Diseases

3. Malaria

4. Antimalarial drug discovery – the path towards eradication

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