Structural Analysis of VDR Complex with ZK168281 Antagonist-Reference-Cited by-同舟云学术

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Structural Analysis of VDR Complex with ZK168281 Antagonist

Published:2020-08-05 Issue:17 Volume:63 Page:9457-9463
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Belorusova Anna Y.¹²³⁴⁵^ORCID,Chalhoub Sandra¹²³⁴,Rovito Daniela¹²³⁴,Rochel Natacha¹²³⁴^ORCID

Affiliation:

1. Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), 67400 Illkirch, France

2. Institut National de La Santé et de La Recherche Médicale (INSERM), U1258, 67400 Illkirch, France

3. Centre National de Recherche Scientifique (CNRS), UMR7104, 67400 Illkirch, France

4. Université de Strasbourg, 67400 Illkirch, France

5. Medicinal Chemistry, Early Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, 431 83 Gothenburg, Sweden

Funder

AstraZeneca

Agence Nationale de la Recherche

Fondation pour la Recherche M?dicale

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c00656

Reference34 articles.

1. Nuclear Receptors and Their Selective Pharmacologic Modulators

2. Vitamin D: Metabolism, Molecular Mechanism of Action, and Pleiotropic Effects

3. The role of vitamin D in the endocrinology controlling calcium homeostasis

4. Vitamin D: Newer Concepts of Its Metabolism and Function at the Basic and Clinical Level

5. Vitamin D and Its Synthetic Analogs

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1. The diverse genomic mechanisms of action of the vitamin D receptor;Feldman and Pike' s Vitamin D;2024

2. Structure function relationships of VDR ligands;Feldman and Pike' s Vitamin D;2024

3. Structural basis for ligand activity in vitamin D receptor;Feldman and Pike' s Vitamin D;2024

4. Further Studies on the Highly Active Des-C-Ring and Aromatic-D-Ring Analogues of 1α,25-Dihydroxyvitamin D₃ (Calcitriol): Refinement of the Side Chain;Journal of Medicinal Chemistry;2023-11-01

5. Syntheses of 25-Adamantyl-25-alkyl-2-methylidene-1α,25-dihydroxyvitamin D3 Derivatives with Structure–Function Studies of Antagonistic and Agonistic Active Vitamin D Analogs;Biomolecules;2023-07-06

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