Design, Synthesis, and Biological Evaluation of Membrane-Active Bakuchiol Derivatives as Effective Broad-Spectrum Antibacterial Agents

Author:

Li Hongxia1,Liu Jiayong1ORCID,Liu Chuan-Fa2ORCID,Li Haizhou1,Luo Jiachun1,Fang Shanfang1,Chen Yongzhi1,Zhong Rongcui1,Liu Shouping1ORCID,Lin Shuimu1ORCID

Affiliation:

1. Key Laboratory of Molecular Target & Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences & the Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou 511436, P.R. China

2. School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 637551, Singapore

Funder

National Natural Science Foundation of China

Talent Fund for High-Level University Construction of Guangzhou

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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