Can Invalid Bioactives Undermine Natural Product-Based Drug Discovery?-Reference-Cited by-同舟云学术

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Can Invalid Bioactives Undermine Natural Product-Based Drug Discovery?

Published:2015-10-27 Issue:5 Volume:59 Page:1671-1690
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bisson Jonathan,McAlpine James B.,Friesen J. Brent¹,Chen Shao-Nong,Graham James,Pauli Guido F.

Affiliation:

1. Physical Sciences Department, Rosary College of Arts and Sciences, Dominican University, River Forest, Illinois 60305, United States

Funder

Office of Dietary Supplements

National Institute of Dental and Craniofacial Research

National Institute of Allergy and Infectious Diseases

National Center for Complementary and Integrative Health

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b01009

Reference123 articles.

1. Quantitative Analyses of Aggregation, Autofluorescence, and Reactivity Artifacts in a Screen for Inhibitors of a Thiol Protease

2. New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays

3. A Common Mechanism Underlying Promiscuous Inhibitors from Virtual and High-Throughput Screening

4. New perspectives on natural products in TB drug research

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