Development of Heat Shock Protein (Hsp90) Inhibitors To Combat Resistance to Tyrosine Kinase Inhibitors through Hsp90–Kinase Interactions

Author:

Wang Meining1,Shen Aijun2,Zhang Chi3,Song Zilan1,Ai Jing2,Liu Hongchun2,Sun Liping3,Ding Jian2,Geng Meiyu2,Zhang Ao1

Affiliation:

1. CAS Key Laboratory of Receptor Research, Synthetic Organic & Medicinal Chemistry Laboratory, Shanghai Institute of Materia Medica (SIMM), Chinese Academy of Sciences, 555 Zuchongzhi Lu, Building 3, Room 426, Pudong, Shanghai 201203, China

2. Division of Anti-tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica (SIMM), Chinese Academy of Sciences, Shanghai 201203, China

3. Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China

Funder

Ministry of Science and Technology of the People's Republic of China

National Natural Science Foundation of China

Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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