Pyrrolo[3,4-c]pyridine-1,3(2H)-diones: A Novel Antimycobacterial Class Targeting Mycobacterial Respiration

Author:

van der Westhuyzen Renier1,Winks Susan1,Wilson Colin R.1,Boyle Grant A.1,Gessner Richard K.1,Soares de Melo Candice1,Taylor Dale2,de Kock Carmen2,Njoroge Mathew3,Brunschwig Christel3,Lawrence Nina1,Rao Srinivasa P.S.4,Sirgel Frederick5,van Helden Paul5,Seldon Ronnett1,Moosa Atica6,Warner Digby F.67,Arista Luca8,Manjunatha Ujjini H.4,Smith Paul W.4,Street Leslie J.1,Chibale Kelly137

Affiliation:

1. Drug Discovery and Development Centre (H3D), Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa

2. Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Observatory 7925, South Africa

3. South African Medical Research Council Drug Discovery and Development Research Unit, Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa

4. Novartis Institute for Tropical Diseases (NITD), 10 Biopolis Road, Chromos no. 05-01, Singapore 138670, Singapore

5. DST/NRF Centre of Excellence in Biomedical TB Research, SA MRC Centre for TB Research, Division of Molecular Biology and Human Genetics, Faculty of Health Sciences, Stellenbosch University, Tygerberg 7505, South Africa

6. MRC/NHLS/UCT Molecular Mycobacteriology Research Unit, Department of Pathology, University of Cape Town, Rondebosch 7701, South Africa

7. Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Rondebosch 7701, South Africa

8. Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland

Funder

National Institute of Allergy and Infectious Diseases

Novartis Foundation

Bill and Melinda Gates Foundation

South African Medical Research Council

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3