Novel β-Carboline/Hydroxamic Acid Hybrids Targeting Both Histone Deacetylase and DNA Display High Anticancer Activity via Regulation of the p53 Signaling Pathway
Author:
Affiliation:
1. State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, P.R. China
2. Department of Pharmacology and Therapeutics, Roswell Park Cancer Institute, Buffalo, New York, USA
Funder
State Key Laboratory of Natural Medicines, China Pharmaceutical University
Jiangsu Province
Government of Jiangsu Province
Priority Academic Program Development of Jiangsu Higher Education Institutions
National Natural Science Foundation of China
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b01052
Reference37 articles.
1. Chemotherapy for colorectal cancer in the elderly
2. Metastatic Colorectal Cancer: Current State and Future Directions
3. Perspectives in the development of hybrid bifunctional antitumour agents
4. A review on medicinal importance, pharmacological activity and bioanalytical aspects of beta-carboline alkaloid “Harmine”
5. Specific inhibition of cyclin-dependent kinases and cell proliferation by harmine
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