Melanin-Concentrating Hormone Receptor 1 Antagonists Lacking an Aliphatic Amine: Synthesis and Structure–Activity Relationships of Novel 1-(Imidazo[1,2-a]pyridin-6-yl)pyridin-2(1H)-one Derivatives

Author:

Igawa Hideyuki1,Takahashi Masashi1,Kakegawa Keiko1,Kina Asato1,Ikoma Minoru1,Aida Jumpei1,Yasuma Tsuneo2,Kawata Yayoi1,Ashina Shuntaro1,Yamamoto Syunsuke1,Kundu Mrinalkanti3,Khamrai Uttam3,Hirabayashi Hideki1,Nakayama Masaharu1,Nagisa Yasutaka4,Kasai Shizuo1,Maekawa Tsuyoshi1

Affiliation:

1. Pharmaceutical Research Division, Takeda Pharmaceutical Co., Ltd., Shonan Research Center, 26-1, Muraoka-Higashi 2-Chome, Fujisawa, Kanagawa 251-8555, Japan

2. CMC Center, Takeda Pharmaceutical Co., Ltd., 17-85, Jusohonmachi 2-Chome, Yodogawa-ku, Osaka 532-8686, Japan

3. TCG Lifesciences Ltd., Block BN, Plot 7, Saltlake Electronics Complex, Sector V, Kolkata 700091, India

4. CVM Marketing Japan Pharma Business Unit, Takeda Pharmaceutical Co., Ltd. 12-10, Nihonbashi 2-Chome, Chuo-ku, Tokyo 103-8686, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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