Discovery of a Teraryl Oxazolidinone Compound (S)-N-((3-(3-Fluoro-4-(4-(pyridin-2-yl)-1H-pyrazol-1-yl)phenyl)-2-oxooxazolidin-5-yl)methyl)acetamide Phosphate as a Novel Antimicrobial Agent with Enhanced Safety Profile and Efficacies-Reference-Cited by-同舟云学术

Discovery of a Teraryl Oxazolidinone Compound (S)-N-((3-(3-Fluoro-4-(4-(pyridin-2-yl)-1H-pyrazol-1-yl)phenyl)-2-oxooxazolidin-5-yl)methyl)acetamide Phosphate as a Novel Antimicrobial Agent with Enhanced Safety Profile and Efficacies

Published:2015-08-17 Issue:16 Volume:58 Page:6389-6409
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Yang Tao¹,Chen Gong¹,Sang Zitai¹,Liu Yuanyuan¹,Yang Xiaoyan¹,Chang Ying¹,Long Haiyue¹,Ang Wei¹,Tang Jianying²,Wang Zhenling¹,Li Guobo¹,Yang Shengyong¹,Zhang Jingren³,Wei Yuquan¹,Luo Youfu¹

Affiliation:

1. State Key Laboratory of Biotherapy/Collaborative Innovation Center for Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan 610041, China

2. Sichuan Good Doctor Pharmaceutical Co., Ltd., Chengdu, Sichuan 610031, China

3. Centre for Infectious Diseases Research, School of Medicine, Tsinghua University, Beijing, 100084, China

Funder

National Natural Science Foundation of China

Program for New Century Excellent Talents in University

Ministry of Science and Technology of the People's Republic of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b00152