Novel Pyrazolo[1,5-a]pyrimidines as Translocator Protein 18 kDa (TSPO) Ligands: Synthesis, in Vitro Biological Evaluation, [18F]-Labeling, and in Vivo Neuroinflammation PET Images
Author:
Affiliation:
1. CEA, I2BM, Service Hospitalier Frédéric Joliot, Orsay, France
2. Inserm/CEA/Université Paris Sud, UMR 1023−ERL 9218 CNRS, IMIV, Orsay, France
3. LGCR, Sanofi, Chilly-Mazarin, France
Funder
Seventh Framework Programme
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b00932
Reference54 articles.
1. Radiolabelled Molecules for Imaging the Translocator Protein (18 kDa) Using Positron Emission Tomography
2. Synthesis and Biological Evaluation of 4-Phenylquinazoline-2-carboxamides Designed as a Novel Class of Potent Ligands of the Translocator Protein
3. Structure–Activity Relationship Refinement and Further Assessment of 4-Phenylquinazoline-2-carboxamide Translocator Protein Ligands as Antiproliferative Agents in Human Glioblastoma Tumors
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