Preparation and Evaluation of Radiolabeled Antibody Recruiting Small Molecules That Target Prostate-Specific Membrane Antigen for Combined Radiotherapy and Immunotherapy-Reference-Cited by-同舟云学术

Preparation and Evaluation of Radiolabeled Antibody Recruiting Small Molecules That Target Prostate-Specific Membrane Antigen for Combined Radiotherapy and Immunotherapy

Published:2016-03-03 Issue:6 Volume:59 Page:2660-2673
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Genady Afaf R.¹²,Janzen Nancy¹,Banevicius Laura¹,El-Gamal Mahmoud¹,El-Zaria Mohamed E.¹,Valliant John F.¹³

Affiliation:

1. Department of Chemistry and Chemical Biology, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4M1, Canada

2. Department of Chemistry, Faculty of Science, Tanta University, 31527 Tanta, Egypt

3. Centre for Probe Development and Commercialization, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada

Funder

Natural Sciences and Engineering Research Council of Canada

Ontario Institute for Cancer Research

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b01881

Reference25 articles.

1. Advances in targeted therapy for unresectable melanoma: New drugs and combinations

2. Anti-programmed death receptor 1 immunotherapy in melanoma: rationale, evidence and clinical potential

3. Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

4. Antibody-Recruiting Molecules: An Emerging Paradigm for Engaging Immune Function in Treating Human Disease

5. Natural DNP-binding immunoglobulins and antibody multispecificity

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