Identification of Highly Promising Antioxidants/Neuroprotectants Based on Nucleoside 5′-Phosphorothioate Scaffold. Synthesis, Activity, and Mechanisms of Action-Reference-Cited by-同舟云学术

Identification of Highly Promising Antioxidants/Neuroprotectants Based on Nucleoside 5′-Phosphorothioate Scaffold. Synthesis, Activity, and Mechanisms of Action

Published:2015-10-16 Issue:21 Volume:58 Page:8427-8443
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Azran Sagit¹,Danino Ortal¹,Förster Daniel²,Kenigsberg Sarah¹,Reiser Georg²,Dixit Mudit¹,Singh Vijay¹,Major Dan T.¹,Fischer Bilha¹

Affiliation:

1. Department of Chemistry and the Lise Meitner-Minerva Center of Computational Quantum Chemistry, Bar-Ilan University, Ramat-Gan 52900, Israel

2. Otto von Guericke University, Leipziger Strasse 44, 39120, Magdeburg, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b00575

Reference61 articles.

1. The Amyloid β Protein Induces Oxidative Damage of Mitochondrial DNA

2. Purinergic signalling in the nervous system: an overview

3. Extracellular ATP and Neurodegeneration

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5. Pharmacological profiles of cloned mammalian P2Y-receptor subtypes

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