An Aggregation Advisor for Ligand Discovery-Reference-Cited by-同舟云学术

An Aggregation Advisor for Ligand Discovery

Published:2015-08-28 Issue:17 Volume:58 Page:7076-7087
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Irwin John J.¹,Duan Da¹,Torosyan Hayarpi¹,Doak Allison K.¹,Ziebart Kristin T.¹,Sterling Teague¹,Tumanian Gurgen¹,Shoichet Brian K.¹

Affiliation:

1. Department of Pharmaceutical Chemistry, University of California, San Francisco, Byers Hall, 1700 4th St, San Francisco, California 94158-2550, United States

Funder

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b01105

Reference48 articles.

1. Development of a Virtual Screening Method for Identification of “Frequent Hitters” in Compound Libraries

2. A High-Throughput Screen for Aggregation-Based Inhibition in a Large Compound Library

3. A Specific Mechanism of Nonspecific Inhibition

4. Colloidal Aggregation Causes Inhibition of G Protein-Coupled Receptors

5. A pharmacological organization of G protein–coupled receptors

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