Structure–Activity Relationship Study of Rakicidins: Overcoming Chronic Myeloid Leukemia Resistance to Imatinib with 4-Methylester-Rakicidin A

Author:

Sang Feng12,Ding Yahui1,Wang Jinghan1,Sun Bingxia1,Sun Jianlei1,Geng Yan13,Zhang Zhang4,Ding Ke4,Wu Ling-Ling13,Liu Jian-Wei1,Bai Cuigai3,Yang Guang1,Zhang Quan1,Li Lu-Yuan1,Chen Yue1

Affiliation:

1. The State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300071, People’s Republic of China

2. School of Life Sciences, Shandong University of Technology, Zibo 255049, People’s Republic of China

3. High-throughput Molecular Drug Discovery Center, Tianjin International Joint Academy of BioMedicine, Tianjin 300457, People’s Republic of China

4. State Key Laboratory of Respiratory Diseases, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Science, 190 Kai Yuan Avenue, Guangzhou 510530, People’s Republic of China

Funder

Program for New Century Excellent Talents in University

Nankai University

China Postdoctoral Science Foundation

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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