Synthesis and Evaluation of Novel 7- and 8-Aminophenoxazinones for the Detection of β-Alanine Aminopeptidase Activity and the Reliable Identification of Pseudomonas aeruginosa in Clinical Samples-Reference-Cited by-同舟云学术

Synthesis and Evaluation of Novel 7- and 8-Aminophenoxazinones for the Detection of β-Alanine Aminopeptidase Activity and the Reliable Identification of Pseudomonas aeruginosa in Clinical Samples

Published:2016-05-04 Issue:10 Volume:59 Page:4476-4487
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bedernjak Alexandre F.¹,Zaytsev Andrey V.²,Babolat Michèle²,Cellier Marie²,James Arthur L.³,Orenga Sylvain²,Perry John D.⁴,Groundwater Paul W.¹,Anderson Rosaleen J.¹

Affiliation:

1. Sunderland Pharmacy School, University of Sunderland, Sunderland SR1 3SD, U.K.

2. Department of Microbiology, bioMérieux, 38390 La Balme-les-Grottes, France

3. School of Life Sciences, Northumbria University, Newcastle upon Tyne, NE1 8ST, U.K.

4. Department of Microbiology, Freeman Hospital, Newcastle upon Tyne NE7 7DN, U.K.

Funder

BioMérieux

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b01591

Reference11 articles.

1. Synthesis and testing of chromogenic phenoxazinone substrates for β-alanyl aminopeptidase

2. A DmpA-homologous protein from Pseudomonas sp. is a dipeptidase specific for β-alanyl dipeptides

3. Synthesis and evaluation of novel chromogenic aminopeptidase substrates for microorganism detection and identification

4. Synthesis and evaluation of novel chromogenic peptidase substrates based on 9-(4′-aminophenyl)-10-methylacridinium salts as diagnostic tools in clinical bacteriology

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