Optimization of a Stable Linker Involved DEVD Peptide-Doxorubicin Conjugate That Is Activated upon Radiation-Induced Caspase-3-Mediated Apoptosis

Author:

Chung Seung Woo1,Lee Beom Suk23,Choi Jeong uk1,Kim Seong Who4,Kim In-San3,Kim Sang Yoon23,Byun Youngro15

Affiliation:

1. Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, 151-742 Seoul, South Korea

2. Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, 138-736 Seoul, South Korea

3. Biomedical Research Institute, Korea Institute of Science and Technology, 136-791 Seoul, South Korea

4. Department of Biochemistry and Molecular Biology, Asan Medical Center, University of Ulsan College of Medicine, 138-736 Seoul, South Korea

5. Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergent Science and Technology, Seoul National University, 151-742 Seoul, South Korea

Funder

National Research Foundation of Korea

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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