Monitoring the Progression of Structure–Activity Relationship Information during Lead Optimization-Reference-Cited by-同舟云学术

Monitoring the Progression of Structure–Activity Relationship Information during Lead Optimization

Published:2015-11-16 Issue:9 Volume:59 Page:4235-4244
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Shanmugasundaram Veerabahu¹,Zhang Liying²,Kayastha Shilva³,de la Vega de León Antonio³,Dimova Dilyana³,Bajorath Jürgen³

Affiliation:

1. Center of Chemistry Innovation & Excellence, WorldWide Medicinal Chemistry, Pfizer PharmaTherapeutics Research & Development, Eastern Point Road, Groton, Connecticut 06340, United States

2. Computational Sciences CoE, WorldWide Medicinal Chemistry, Pfizer PharmaTherapeutics Research & Development, 610 Main Street, Cambridge, Massachusetts 06340, United States

3. Department of Life Science Informatics, B-IT, LIMES Program Unit Chemical Biology and Medicinal Chemistry, Dahlmannstr. 2, Rheinische Friedrich-Wilhelms-Universität, D-53113 Bonn, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b01428

Reference15 articles.

1. Advances in multiparameter optimization methods forde novodrug design

2. SAR Monitoring of Evolving Compound Data Sets Using Activity Landscapes

3. Quantifying, Visualizing, and Monitoring Lead Optimization

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