Important Hydrogen Bond Networks in Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor Design Revealed by Crystal Structures of Imidazoleisoindole Derivatives with IDO1-Reference-Cited by-同舟云学术

Important Hydrogen Bond Networks in Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor Design Revealed by Crystal Structures of Imidazoleisoindole Derivatives with IDO1

Published:2015-12-21 Issue:1 Volume:59 Page:282-293
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Peng Yi-Hui¹,Ueng Shau-Hua¹,Tseng Chen-Tso¹,Hung Ming-Shiu¹,Song Jen-Shin¹,Wu Jian-Sung¹,Liao Fang-Yu¹,Fan Yu-Shiou¹,Wu Mine-Hsine¹,Hsiao Wen-Chi¹,Hsueh Ching-Cheng¹,Lin Shu-Yu¹,Cheng Chia-Yi¹,Tu Chih-Hsiang¹,Lee Lung-Chun¹,Cheng Ming-Fu¹,Shia Kak-Shan¹,Shih Chuan¹,Wu Su-Ying¹

Affiliation:

1. Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, 35, Keyan Road, Zhunan, Miaoli County 35053, Taiwan, ROC

Funder

Ministry of Health and Welfare

National Health Research Institutes

National Science Council Taiwan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b01390

Reference50 articles.

1. Inhibitors of indoleamine-2,3-dioxygenase for cancer therapy: can we see the wood for the trees?