Removal of Metabolic Liabilities Enables Development of Derivatives of Procaspase-Activating Compound 1 (PAC-1) with Improved Pharmacokinetics-Reference-Cited by-同舟云学术

Removal of Metabolic Liabilities Enables Development of Derivatives of Procaspase-Activating Compound 1 (PAC-1) with Improved Pharmacokinetics

Published:2015-04-20 Issue:9 Volume:58 Page:4046-4065
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Roth Howard S.¹,Botham Rachel C.¹,Schmid Steven C.¹,Fan Timothy M.¹,Dirikolu Levent¹,Hergenrother Paul J.¹

Affiliation:

1. Department of Chemistry, ‡Department of Veterinary Clinical Medicine, and §Department of Veterinary Biosciences, University of Illinois, Urbana, Illinois 61801, United States

Funder

National Science Foundation

National Cancer Institute

American Chemical Society

Center for Advanced Study, University of Illinois at Urbana-Champaign

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b00413

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