Amphipathicity Determines Different Cytotoxic Mechanisms of Lysine- or Arginine-Rich Cationic Hydrophobic Peptides in Cancer Cells-Reference-Cited by-同舟云学术

Amphipathicity Determines Different Cytotoxic Mechanisms of Lysine- or Arginine-Rich Cationic Hydrophobic Peptides in Cancer Cells

Published:2016-05-26 Issue:11 Volume:59 Page:5238-5247
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Liu Xiaoli¹²,Cao Rui¹,Wang Sha¹³,Jia Junli¹,Fei Hao¹

Affiliation:

1. CAS Key Laboratory of Nano-Bio Interface, Division of Nanobiomedicine, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, 398 Ruoshui Road, Suzhou Industrial Park, Suzhou, Jiangsu 215123, P. R. China

2. School of Life Science, Shanghai University, 99 Shangda Road, Baoshan District, Shanghai 200444, P. R. China

3. School of Pharmacy, Xi’an Jiaotong University, Xi’an, Shaanxi 710061, P. R. China

Funder

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b02016

Reference51 articles.

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4. New Lytic Peptides Based on the d,l-Amphipathic Helix Motif Preferentially Kill Tumor Cells Compared to Normal Cells

5. Cationic amphiphilic peptides with cancer-selective toxicity

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