Synthesis of Tridecaptin–Antibiotic Conjugates with in Vivo Activity against Gram-Negative Bacteria

Author:

Cochrane Stephen A.1,Li Xuefeng2,He Sisi2,Yu Min2,Wu Min2,Vederas John C.1

Affiliation:

1. Department of Chemistry, University of Alberta, Edmonton, Alberta, T6G 2G2, Canada

2. Department of Biomedical Sciences, University of North Dakota School of Medicine and Health Sciences, Grand Forks, North Dakota 58203-9037, United States

Funder

Alberta Innovates - Health Solutions

National Institute of Allergy and Infectious Diseases

Flight Attendant Medical Research Institute

Natural Sciences and Engineering Research Council of Canada

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Reference26 articles.

1. O’Neill, J., Chair.Review on Antimicrobial Resistance: Tackling a Crisis for the Health and Wealth of Nation.HM Government, Wellcome Trust:London, 2014

2. Systems-level antimicrobial drug and drug synergy discovery

3. Antibiotics in the clinical pipeline in 2013

4. Antibiotics currently in clincal development.The PEW Charitable Trusts:Philadelphia, PA, 2015.

5. Natural product and natural product derived drugs in clinical trials

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