Design, Synthesis, and Structure–Activity Relationship Study of Novel Indole-2-carboxamide Derivatives as Anti-inflammatory Agents for the Treatment of Sepsis

Author:

Liu Zhiguo1,Tang Longguang12,Zhu Heping1,Xu Tingting3,Qiu Chenyu1,Zheng Suqing1,Gu Yugui4,Feng Jianpeng1,Zhang Yali1,Liang Guang1

Affiliation:

1. Chemical Biology Research Center at School of Pharmaceutical Sciences, Wenzhou Medical University, 1210 University Town, Wenzhou, Zhejiang 325035, China

2. Center for Molecular Imaging and Translational Medicine, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen 361102, China

3. The Second Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China

4. Chemical Biology Section in WMU−WU Joint Research Centre, Wenzhou University, Wenzhou, Zhejiang 325035, China

Funder

National Natural Science Foundation of China

Scientific Research Foundation, Wenzhou Medical University

Public Welfare Science and Technology Project of Wenzhou

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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