Indole Glucocorticoid Receptor Antagonists Active in a Model of Dyslipidemia Act via a Unique Association with an Agonist Binding Site.-Reference-Cited by-同舟云学术

Indole Glucocorticoid Receptor Antagonists Active in a Model of Dyslipidemia Act via a Unique Association with an Agonist Binding Site.

Published:2015-08-07 Issue:16 Volume:58 Page:6607-6618
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Luz John G.¹,Carson Matthew W.²,Condon Bradley¹,Clawson David²,Pustilnik Anna¹,Kohlman Daniel T.²,Barr Robert J.²,Bean James S.²,Dill M. Joelle²,Sindelar Dana K²,Maletic Milan¹,Coghlan Michael J.²

Affiliation:

1. Eli Lilly Biotechnology Center, 10300 Campus Point Drive, Suite 200, San Diego, California 92121 United States

2. Lilly Research Laboratories, A Division of Eli Lilly & Co., Lilly Corporate Center, Indianapolis, Indiana 46285 United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b00736

Reference53 articles.

1. Selective modulation of the glucocorticoid receptor can distinguish between transrepression of NF-κB and AP-1

2. Molecular Control of Immune/Inflammatory Responses: Interactions Between Nuclear Factor-κB and Steroid Receptor-Signaling Pathways

3. CBP (CREB Binding Protein) Integrates NF-κB (Nuclear Factor-κB) and Glucocorticoid Receptor Physical Interactions and Antagonism

4. Maps and legends: The quest for dissociated ligands of the glucocorticoid receptor

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