Highly Potent and Selective MT2 Melatonin Receptor Full Agonists from Conformational Analysis of 1-Benzyl-2-acylaminomethyl-tetrahydroquinolines-Reference-Cited by-同舟云学术

Highly Potent and Selective MT2 Melatonin Receptor Full Agonists from Conformational Analysis of 1-Benzyl-2-acylaminomethyl-tetrahydroquinolines

Published:2015-09-14 Issue:18 Volume:58 Page:7512-7525
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Spadoni Gilberto¹,Bedini Annalida¹,Lucarini Simone¹,Mari Michele¹,Caignard Daniel-Henri²,Boutin Jean A.²,Delagrange Philippe²,Lucini Valeria³,Scaglione Francesco³,Lodola Alessio⁴,Zanardi Franca⁴,Pala Daniele⁴,Mor Marco⁴,Rivara Silvia⁴

Affiliation:

1. Dipartimento di Scienze Biomolecolari, Università degli Studi di Urbino “Carlo Bo”, Piazza Rinascimento 6, I-61029 Urbino, Italy

2. Institut de Recherches Servier, 125 Chemin de Ronde, F-78290 Croissy sur Seine, France

3. Dipartimento di Biotecnologie Mediche e Medicina Traslazionale, Università degli Studi di Milano, Via Vanvitelli 32, I-20129 Milano, Italy

4. Dipartimento di Farmacia, Università degli Studi di Parma, Parco Area delle Scienze 27/A, I-43124 Parma, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b01066

Reference42 articles.

1. Melatonin—A pleiotropic, orchestrating regulator molecule

2. Melatonin: therapeutic and clinical utilization

3. Therapeutic uses of melatonin and melatonin derivatives: a patent review (2012 – 2014)

4. Clinical Uses of Melatonin: Evaluation of Human Trials

5. Melatonin: Signaling mechanisms of a pleiotropic agent

Cited by 50 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Industrial and academic approaches to the search for alternative melatonin receptor ligands: An historical survey;Journal of Pineal Research;2024-04-29

2. Melatonin receptor structure and signaling;Journal of Pineal Research;2024-04

3. Designing of target‐specific N‐substituted tetrahydroquinoline derivatives as potent mTOR inhibitors via integrated structure‐guided computational approaches;ChemistrySelect;2024-02-14

4. Binding and unbinding of potent melatonin receptor ligands: Mechanistic simulations and experimental evidence;Journal of Pineal Research;2024-01-31

5. Iridium-catalyzed reductive β-alkylation of (iso)quinoline derivatives by an in situ enone-trapping strategy;Organic & Biomolecular Chemistry;2024