Discovery of Narrow Spectrum Kinase Inhibitors: New Therapeutic Agents for the Treatment of COPD and Steroid-Resistant Asthma-Reference-Cited by-同舟云学术

Discovery of Narrow Spectrum Kinase Inhibitors: New Therapeutic Agents for the Treatment of COPD and Steroid-Resistant Asthma

Published:2016-02-04 Issue:5 Volume:59 Page:1727-1746
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Onions Stuart T.¹,Ito Kazuhiro²,Charron Catherine E.²,Brown Richard J.¹,Colucci Marie¹,Frickel Fritz²,Hardy George²,Joly Kevin¹,King-Underwood John³,Kizawa Yasuo⁴,Knowles Ian⁵,Murray P. John²,Novak Andrew¹,Rani Anjna¹,Rapeport Garth²,Smith Alun¹,Strong Peter²,Taddei David M.¹,Williams Jonathan G.¹

Affiliation:

1. Sygnature Discovery Limited, Biocity, Nottingham NG1 1GF, United Kingdom

2. RespiVert Limited, 2 Royal College Street, The London Bioscience Innovation Centre, London NW1 0NH, United Kingdom

3. CompChem Resource, Old Cottage Hospital, Homend, Ledbury, Herefordshire HR8 1ED, United Kingdom

4. Department of Physiology and Anatomy, Nihon University School of Pharmacy, 7-7-1, Narashinodai, Funabashi, Chiba 274-8555, Japan

5. Pneumolabs UK Limited, Harrow, Middlesex HA1 3UJ, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b01029

Reference51 articles.

1. Corticosteroid Resistance in Airway Disease

2. Review article: steroid resistance in inflammatory bowel disease - mechanisms and therapeutic strategies

3. Role of Latent Viral Infections in Chronic Obstructive Pulmonary Disease and Asthma

4. Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease

5. Inhaled corticosteroids for stable chronic obstructive pulmonary disease

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