Development of Noncovalent Small-Molecule Keap1-Nrf2 Inhibitors by Fragment-Based Drug Discovery-Reference-Cited by-同舟云学术

Development of Noncovalent Small-Molecule Keap1-Nrf2 Inhibitors by Fragment-Based Drug Discovery

Published:2022-10-20 Issue:21 Volume:65 Page:14481-14526
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Narayanan Dilip¹,Tran Kim T.¹,Pallesen Jakob S.¹^ORCID,Solbak Sara M. Ø.¹^ORCID,Qin Yuting¹,Mukminova Elina¹,Luchini Martina¹,Vasilyeva Kristina O.¹,González Chichón Dorleta¹^ORCID,Goutsiou Georgia¹,Poulsen Cecilie²,Haapanen Nanna¹,Popowicz Grzegorz M.³⁴,Sattler Michael³⁴^ORCID,Olagnier David²^ORCID,Gajhede Michael¹^ORCID,Bach Anders¹^ORCID

Affiliation:

1. Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark

2. Department of Biomedicine, Faculty of Health, Aarhus University, 8000 Aarhus C, Denmark

3. Institute of Structural Biology, Helmholtz Zentrum München, 85764 Neuherberg, Germany

4. Bavarian NMR Center, Department of Chemistry, Technical University of Munich, 85747 Garching, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c00830

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1. Targeting Oxidative Stress in Stroke

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