New Glucosamine-Based TLR4 Agonists: Design, Synthesis, Mechanism of Action, and In Vivo Activity as Vaccine Adjuvants-Reference-Cited by-同舟云学术

New Glucosamine-Based TLR4 Agonists: Design, Synthesis, Mechanism of Action, and In Vivo Activity as Vaccine Adjuvants

Published:2023-02-02 Issue:4 Volume:66 Page:3010-3029
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Romerio Alessio¹,Gotri Nicole¹,Franco Ana Rita¹,Artusa Valentina¹,Shaik Mohammed Monsoor¹,Pasco Samuel T.²^ORCID,Atxabal Unai²,Matamoros-Recio Alejandra³^ORCID,Mínguez-Toral Marina³^ORCID,Zalamea Juan Diego²,Franconetti Antonio²^ORCID,Abrescia Nicola G. A.²⁴^ORCID,Jimenez-Barbero Jesus²⁴⁵⁶^ORCID,Anguita Juan²⁴,Martín-Santamaría Sonsoles³^ORCID,Peri Francesco¹^ORCID

Affiliation:

1. Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza, 2, 20126 Milano, Italy

2. Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), 48160 Derio, Bizkaia, Spain

3. Centro de Investigaciones Biológicas Margarita Salas CSIC, C/Ramiro de Maeztu, 9, 28040 Madrid, Spain

4. Ikerbasque, Basque Foundation for Science, Plaza Euskadi 5, 48009 Bilbao, Bizkaia, Spain

5. Department of Organic Chemistry, II Faculty of Science and Technology, EHU-UPV, 48940 Leioa, Spain

6. Centro de Investigación Biomédica En Red de Enfermedades Respiratorias, 28029 Madrid, Spain

Funder

Ministerio de Asuntos Econ?micos y Transformaci?n Digital, Gobierno de Espa?a

Agencia Estatal de Investigaci?n

European Regional Development Fund

H2020 Marie Sklodowska-Curie Actions

Instituto de Salud Carlos III

Department of Biotechnology and Biosciences BtBs, University of Milano-Bicocca

National Interuniversity Consortium for Innovative Synthesis Methodologies and Processes CINMPIS

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c01998

Reference64 articles.

1. Vaccines and vaccination: history and emerging issues

2. The history of the smallpox vaccine

3. Real-world effectiveness of COVID-19 vaccines: a literature review and meta-analysis

4. Overview of Vaccine Adjuvants: Introduction, History, and Current Status

5. Understanding modern-day vaccines: what you need to know

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