Structure–Activity Relationship and Neuroprotective Activity of 1,5-Dihydro-2H-naphtho[1,2-b][1,4]diazepine-2,4(3H)-diones as P2X4 Receptor Antagonists-Reference-Cited by-同舟云学术

Structure–Activity Relationship and Neuroprotective Activity of 1,5-Dihydro-2H-naphtho[1,2-b][1,4]diazepine-2,4(3H)-diones as P2X4 Receptor Antagonists

Published:2022-09-23 Issue:20 Volume:65 Page:13967-13987
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Toti Kiran S.¹,Verma Rajkumar²,McGonnigle Michael J.²,Gamiotea Turro Daylin²,Wen Zhiwei¹^ORCID,Lewicki Sarah A.¹,Liang Bruce T.³,Jacobson Kenneth A.¹^ORCID

Affiliation:

1. National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, Maryland 20892-0810, United States

2. Department of Neuroscience, UConn School of Medicine, Farmington, Connecticut 06032, United States

3. Calhoun Cardiology Center, UConn School of Medicine, Farmington, Connecticut 06032, United States

Funder

U.S. Department of Health and Human Services

American Heart Association

U. S. Department of Health and Human Services

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c01197

Reference51 articles.

1. P2X4 receptors, immunity, and sepsis

2. P2X4 Receptor Function in the Nervous System and Current Breakthroughs in Pharmacology

3. Elevated hydrostatic pressure stimulates ATP release which mediates activation of the NLRP3 inflammasome via P2X4 in rat urothelial cells

4. Role of P2X4 Receptor in Mouse Voiding Function

5. P2X4 Receptor Reporter Mice: Sparse Brain Expression and Feeding-Related Presynaptic Facilitation in the Arcuate Nucleus

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